ADAMTS13: AN EMERGING TARGET IN STROKE THERAPY

ADAMTS13: An Emerging Target in Stroke Therapy

Thrombosis is the predominant underlying mechanism of acute ischemic stroke (AIS).Though thrombolysis with tPA has been proven to be effective in treating AIS within the time window, the majority of AIS patients fail to receive tPA due to various reasons.Current medical therapies for AIS have limited efficacy and pose a risk of intracerebral hemorr

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Numerical and experimental investigation on the effect of retrograde vaporization on fines migration and drift in porous oil reservoir: roles of phase change heat transfer and saturation

Abstract Retrograde vaporization effects on oil production are nearly unprecedented to reservoir engineering community, and its relation to formation damage should be explored.For this purpose, this paper elucidates the importance and role of this phenomenon and its phase change heat transfer (PCHT) on fines migration and subsequent, permeability d

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Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Benfotiamine in Healthy Subjects

Lei Sheng,1,* Wei Cao,2,* Pingping Lin,3 Weili Chen,1 Hongrong Xu,1 Chunjiu Zhong,4 Fei Yuan,1 Hanjing Chen,1 Hui Li,1 Chao Liu,1 Mengjie Yang,1 Xuening Li1 1Department of Clinical Pharmacology, Zhongshan Hospital, Fudan University, Shanghai, 200032, People’s Republic of China; 2Shanghai Rixin Biotechnology Co., Ltd, Shanghai, 200237, People&

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